Never, Never Land
Weighing in on AZT for kids
Question AZT for Babies and People Get Hot Under the Collar

Considering the many side effects of the AIDS drug AZT, the question of giving it to pregnant women should be weighed carefully instead of being blindly accepted. (ABCNEWS.com)




By Nicholas Regush
ABCNEWS.com
Passions can run high in scientific circles when questions are raised about conventional thinking in AIDS research. The use of the anti-HIV drug AZT in children of HIV-positive mothers is just such an issue.
     Consider the telephone call I made this week to Dr. Mark Wainberg, head of the International AIDS Society: I had called Wainberg, who does AIDS research at Montreal’s Jewish General Hospital, to interview him on the science underlying the view that HIV-positive women should be given AZT and that their newborns should also be put on the drug.
     (Last week, I began this series by writing about HIV-positive women and their supporters who are taking action in the courts to prevent government authorities from seizing their children if they don’t agree to AZT treatments. Closely related is the question of whether HIV is the cause of AIDS, an issue I will deal with next week.)

Holocaust Equation
I called Wainberg because he had been quoted in the Ottawa Citizen, a major Canadian daily, saying that the dissidents were “fringe people,” and that “There are people out there who deny that the Holocaust happened. Do we want to give them equal credibility?” This article quoting Wainberg had been circulated on the Web. That’s how I learned about it.
     Did Wainberg really make the Holocaust comment? If so, did he really believe a comparison between mothers fighting for their rights in the courts and those denying the Holocaust was valid? If he indeed felt so strongly, then maybe he could document the AZT science underlying his views.
     Not only did Wainberg verify what he had said in regard to the Holocaust in the Ottawa Citizen, but he began shouting at me, saying that if I wrote anything at all on this issue, I would be a “child murderer.” He threatened that if I wrote anything, he would do everything possible to get me fired from my column and my “bosses” fired. He taunted me, saying that I wouldn’t have the guts to print these comments.
     I asked him if he therefore believed that this AZT issue should never be reported by the media. “Never,” he continued to shout. “Absolutely never.” He then went on to condemn me again and again as a “murderer.” He also told me that he considered any other journalist raising questions about the use of AZT in children of HIV-positive mothers to be a child killer.

Just Don’t Ask
Wainberg, a well-recognized AIDS researcher who is one of the developers of the anti-HIV drug 3TC, never once asked me what science questions I wanted to explore with him, and I could barely get a word in edgewise. He had remembered me from more than a decade ago as a Canadian medical reporter who had included nonconventional features and commentaries on AIDS among my more mainstream AIDS stories. Though Wainberg had taken issue with some of my reporting in those days, I had been totally unprepared for this week’s savage assault on anyone (including myself) who had questions about AZT treatment in pregnant HIV-positive women and their newborns.
     Considering that there is usually room for argument on scientific studies, that there are reasonable fears about the potentially powerful side effects of AIDS drugs, and that there may be legitimate concerns about human rights involved in such a complex situation, I could only shake my head in amazement when I put the phone down. Given that other scientists have also shown strong emotion in denouncing challenges to AIDS orthodoxy, it can make you wonder what in the world is happening to scientific debate.

Final Answers?
One key study was published on Nov. 3, 1994, in the New England Journal of Medicine. It showed that HIV-infected mothers who received AZT gave birth to 13 HIV-positive infants, while mothers on placebos gave birth to 40 HIV-positive infants. This small study was stopped early because of the significant difference between the two groups and the results were immediately touted as grounds for making AZT standard therapy for HIV-positive mothers and their newborns.
    But no study comes with all the facts. The authors of the NEJM article note, for example, that the risks and the benefits of initiating (AZT) treatment during the first trimester of pregnancy, after 34 weeks’ gestation, or in labor, or of treating only the newborn were not assessed. In an editorial accompanying the study, the authors state: “The results, however, raise many questions about the mechanism of action of (AZT), the timing of transmission, the effectiveness of the regimen in women with clinical characteristics that differ from those women in the trial, the long-term effects of exposure to (AZT) during pregnancy, and the type of counseling that is appropriate to ensure that HIV-infected women understand the benefits, risks and uncertainties of the therapy.”

No Absolutes Except One
The authors also note that in its recommendations for AZT therapy, the public health service emphasizes “the need for a thorough discussion of the benefits and risks… The final decision on therapy should be made by the woman in consultation with her health care provider.” I might add, a health provider who is properly informed.
     No study has since been published that should change the spirit of that recommendation. While some proponents speak of the steady decline of infant and child AIDS cases after a 1992 peak, factors such as declining births to HIV-positive women and better prenatal care may have played a role. (I’ll explore other factors related to the issue of AIDS causation next week.)
     Then there are the voluminous reports of adverse reactions to AZT to consider, including the drug’s ability to damage bone marrow, kill growing cells (particularly immune cells) by interrupting their synthesis of DNA (life’s blueprint), and to establish itself in DNA with the potential for long-term consequences, which includes the possibility of cancers.
     Should there be widespread reporting and discussion about this entire issue? Absolutely!

Nicholas Regush Nicholas Regush produces medical features for ABCNEWS. In his weekly column, published Wednesdays, he looks at medical trouble spots, heralds innovative achievements and analyzes health trends that may greatly influence our lives. His latest book is The Breaking Point: Understanding Your Potential for Violence.

  Readers React
Opinions on Second Opinion


     The only thing I’ve seen in memory that resembles a holocaust has been the war on AIDS. It is GENOCIDE of homosexual and drug users at a government level. There is no science in the HIV = AIDS hypothesis, and the use of AZT on any human life is MURDER. The 35 billion wasted on HIV research would have been better spent in cleaning up the NIH, the NCI, the CDC and the FDA, and the ones that hold the strings, that is the pharmaceutical industry that cares about one thing only and that is MONEY. At the expense of human life. It’s bad science in the hands of bad government.

— Scott   


     The heated exchange with Dr. Wainberg reminds me of an incident. In 1995, a manuscript of mine was accepted by a peer-reviewed AIDS journal for publication. But my manuscript was not published as promised and was released back to me eventually because it was deemed to be too controversial. You have struck a blow for little people like me. I thank you. Winston Churchill said “This is not the end, nor the beginning of the end. Perhaps it is just the end of the beginning.” The HIV industry, a monster created by government funding, is finally going to be examined critically.
— Ching-Chee   


     Who knows if AZT has side effects on unborn children? As you brashly state on many occasions, there is no proof of that whatsoever… Above and beyond any deleterious effects of AZT, don’t you think that we are better off taking our chances with AZT than allowing more children to be born with HIV, a disease which is tantamount to a death sentence? It doesn’t seem like there’s any debate here. Drugs like chemotherapy agents have terrible side effects… are you going to argue that patients should eschew those as well and choose certain death instead? Once again, you’re barking up the wrong tree, Nickie.
— Name Withheld   


     Bravo! This article is way overdue. I know the Tysons personally, having photographed them when Felix was only 10 weeks old. Their ordeal is a travesty of both justice and of medicine. I sincerely hope there is more to come on the HIV lie.
— Peter   


     It is very refreshing to see a member of the mainstream media representing the HIV = AIDS hypothesis in an objective way. Here in Britain the media is mired in stultifying conformity to the establishment line, and questioning attitudes only figure amongst the disenfranchised. It is of some comfort to note that some media professionals have the intellectual incisiveness to pierce through the bleak scenario that is HIV = AIDS.
— John   


     Thank you so much for confronting the medical orthodoxy on AZT use in pregnancy and childhood. For those of us in the HIV dissident community, reading such commentary is so heartening — finally someone in the press is listening! I also applaud ABC News for supporting your work, especially in an age when direct-to-consumer pharmaceutical advertising is seriously threatening journalistic objectivity. I must urge pregnant women NEVER to submit to an HIV test. Pregnancy is one of those conditions that may cause a ‘false positive’ test (that is if you believe in the existence of HIV), which may result in you losing custody of your child if you refuse to give AZT or try to breast-feed. As a pregnant adult, you still have the right to refuse a test; while as a parent, your ability to decide medical treatment for your fetus/child is very much in doubt. Please do not discount the risk of losing your child to the courts or losing your shirt trying to defend your family against the encroachment of medical and government authorities.
— Beth   


S U M M A R Y

Is skepticism about using AZT in babies of HIV-positive mothers akin to murder?

In This Series
Second Opinion: Why Parents Refuse AZT for Kids

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Drug Cuts Mother to Child AIDS Risk

AZT Lessens AIDS Passing Risk

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