Health Education AIDS Liaison, Toronto

AZT
(RETROVIR or ZIDOVUDINE)


"It was often difficult to distinguish adverse events possibly associated with zidovudine [AZT] administration from the underlying signs of HIV disease" - Physician's Desk Reference, 1994

AZT LABEL WARNING: TOXIC by inhalation, in contact with skin and if swallowed. Target organ(s): Blood bone marrow. ...(etc.)

THIS IS AN ACTUAL COPY OF AN AZT LABEL
This label has appeared on bottles containing as little as 25 milligrams,
a small fraction (1/20-1/50) of a patients daily prescribed dose.

Is the conventional view and treatment of AIDS
the answer or part of the PROBLEM?

"WARNING: RETROVIR (ZIDOVUDINE) [=AZT] MAY BE ASSOCIATED WITH HEMATOLOGIC TOXICITY INCLUDING GRANULOCYTOPENIA AND SEVERE ANEMIA PARTICULARLY IN PATIENTS WITH ADVANCED HIV DISEASE (SEE WARNINGS).
PROLONGED USE OF RETROVIR [=AZT] HAS BEEN ASSOCIATED WITH SYMPTOMATIC MYOPATHY SIMILAR TO THAT PRODUCED BY HUMAN IMMUNODEFICIENCY VIRUS. RARE OCCURRENCES OF LACTIC ACIDOSIS IN THE ABSENCE OF HYPOXEMIA, AND SEVERE HEPATOMEGALY WITH STEATOSIS HAVE BEEN REPORTED WITH THE USE OF ANTIRETROVIRAL NUCLEOSIDE ANALOGUES, INCLUDING RETROVIR AND ZALCITABINE, AND ARE POTENTIALLY FATAL (SEE WARNINGS)."

- from Glaxo Welcome AZT product information


CAN AZT CAUSE AIDS?
"The most toxic drug that has ever been licensed for long term consumption in the free world. ... AZT is a prescription drug and according to the manufacturer itself it causes symptoms that are indistinguishable from AIDS. So I would say it is not arrogant for me to say that AZT is AIDS by prescription."

- Dr Peter Duesberg
professor of molecular and cell biology,
University of California at Berkeley

WHAT ARE THE EFFECTS OF AZT?
"Excruciating headaches; severe nausea; muscular pain; wasting of the muscles; damage to kidneys and nerves; excruciating pains in the legs; encephalitis; severe anemia requiring transfusions to stay alive; lymphoma (cancer); cancer in 49% of cases, versus 2% incidence in non AZT group; liver damage; nail dyschromia (fingernails turn black); insomnia; impotence; dementia; mania; ataxia (failure of muscular coordination); seizures; alopecia (hair falls out). It is a fairly well established fact that AZT was designed to kill the bone marrow. It causes neutropenia or leukopenia (loss of white blood cells) or bone marrow aplasia. Bone marrow toxicity. White blood cells are the basis of the immune system. T cells, granulocytes, those are all parts of the immune system. You kill those with AZT and the immune system is gone."

- Harvey Bialy
Research Editor Bio/Technology Science Journal

No scientific studies for any of the nucleoside analogues (DDI, 3TC, D4T etc.) has proven clinical benefits (improved health) for patients as compared to a similar group of HIV positive people who do not take the drugs. Long Term Survivors typically avoid "anti-HIV" drugs. The lists of side effects for all the nucleoside analogues are long. All nucleoside analogues have to be very similar molecules in order to do their very specific job. If there are serious side effects with one, there are certain to be with the others. ASK YOUR DOCTOR FOR THE FULL PRODUCT INFORMATION AND READ IT. And remember, your doctor is working for you. If you think the drugs are not for you, don't be pressured. You can always shop around to find a doctor who respects your decisions (see Doctors).

Is AZT an "anti-retroviral"?
No. AZT was developed back in the 1960's as a cancer chemotherapy and was shelved because it failed in animal experiments. Also, Glaxo-Wellcome now wants to market it as a treatment for psoriasis and leukemia.

Inflammatory Reactions in HIV-1-Infected Persons after Initiation of Highly Active Antiretroviral Therapy
Joseph A. DeSimone, MD; Roger J. Pomerantz, MD; and Timothy J. Babinchak, MD
Ann Intern Med. 2000;133:447-454.

"It is possible […] that HAART may actually promote the clinical expression and development of such infections, as well as AIDS-related malignant conditions and other noninfectious diseases" This is a review article with 95 references, where authors list several opportunistic infections and malignancies usually known as AIDS defining conditions that afflicted patients only after initiation of HAART therapy lowered viral load and increased CD4 cell counts. HIV researchers have created an ironic new name for this IATROGENIC AIDS: "Immune Restoration Syndrome".

No more cocktails
New Scientist magazine, 16 December 2000.
Four years of "hit hard, hit early" HIV treatment may be on the way out in the US, as evidence mounts of the drugs' serious side effects. AIDS experts in the US are about to complete a humiliating U-turn when the Department of Health and Human Services launches its revised HIV treatment guidelines in January.

Can AZT & other anti-HIV drugs cause AIDS?
By Matthew Irwin, MD
The truth is that AZT, ddI, ddC , protease inhibitors and other drugs termed "antiretrovirals" have not been found in any controlled studies to show proven clinical benefits for HIV/AIDS patients. Even more alarming, there is plenty of evidence that these drugs have been found to cause the very symptoms they are meant to cure. Are the effects of AZT and other "antiretrovirals" being blamed on HIV?

Concerns About AZT (aka Zidovudine, ZDV, Retrovir - some quotes also related to other nucleoside analogs)
compiled by David Crowe of the Alberta Reappraising AIDS Society
Dozens of reasons why you might not want to follow the doctor's orders. Quotes and citations mostly from the scientific literature.

AZT makes babies sick
Here is one of many reports on the lack of clinical benefits of AZT treatment of HIV positive children. Dr. Rasnick shows how some HIV researchers employ the logic Alice encountered through the looking glass to come to their conclusions. Even though more than twice as many HIV+ babies soon became sick after birth to AZT treated HIV positive mothers as compared to HIV positive babies of non-medicated mothers, the researchers came up with some twisted rationale to conclude that AZT was beneficial.

Debating AZT: Mbeki and the AIDS drug controversy
By Anthony Brink   Foreword by Martin Welz
This book is hot off the press, January 2001.
"On 28 October 1999, South African President Thabo Mbeki ordered an enquiry into the safety of the AIDS drug AZT. He did so after reading this debate. Debating AZT has now been updated to reveal the President’s remarkable personal involvement in the subsequent controversy. It also takes a critical look at the roles of rape survivor Charlene Smith, acting Constitutional Court Justice Edwin Cameron, and AIDS Law Project director Mark Heywood, and it exposes the dereliction of the medical experts and journalists on whom the South African public has relied. Described by South Africa’s top investigative journalist, Martin Welz, as “extraordinary”, Debating AZT tells the inside story and provides the shocking facts."

BBC Panorama Expose on AZT/Wellcome
On Monday 18th March, 1996 the BBC's flagship current-affairs programme Panorama dedicated a complete edition to an examination of the controversy around the approval and use of "anti-HIV" drugs such as AZT, and the mounting evidence that while they offer no clinical benefits, their toxic side effects are causing deaths amongst people diagnosed as "HIV positive" or Aids cases.
Complete transcript of the programme.

Dr. Peter Duesberg's paper The Drug-AIDS Hypothesis (1997) has some very revealing sections on AZT:
4. The epidemic of AZT and other anti- HIV/AIDS medications
7.8. Hiding evidence that AZT accelerates death, eleven examples.

The AIDS dilemma: drug diseases blamed on a passenger virus [abstract] FULL TEXT (pdf file)
Peter Duesberg, David Rasnick
Genetica 104(2): 85-132, 1998

Critical Analysis of the Pharmacology of AZT and its Use in AIDS
[pdf version]
Eleni Papadopulos-Eleopulos, Valendar F. Turner, John M. Papadimitriou, David Causer, Helman Alphonso and Todd Miller
Current Medical Research and Opinion Vol.15, supplement

AZT and Cancer
John Lauritsen, New York Native October 19th, 1987
Although this article is several years old, the questions it asks have never been answered, and consequently is still of great importance.

"Mythical" dangers of AIDS drug are all too real
John Lauritsen
The article appeared in the Provincetown Banner of 27 August 1998. It is a response to an article by Richard Ferri, a Provincetown nurse and AIDS counsellor. John Lauritsen has followed this drug for over a decade, and written two books exposing AZT lies: Poison By Prescription: The AZT Story (1990) and The AIDS War (1993).

Other articles about AZT

HAART Chart
The scoop on how many antiretorviral takers suffer side effects
compiled by Linda Grinberg and Tim Horn
POZ May 1999

ADVERSE DRUG REACTIONS
Adverse drug reactions (ADRs) are the 4th leading cause of death in the USA, according to a recent study (JAMA 1998; 279: 1200-05). Not only that, ADRs mimic the symptoms of many diseases making them a serious concern for people taking or considering taking "anti- HIV" drugs.




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