Sign the petition

Durban Declaration Rebuttal

Commentary

Dear Robert,

I was very impressed with your response to the Durban declaration. I hope it is widely distributed. It certainly deserves to be.

I have a few observations which I think might strenghten your response, should you choose to incorporate them.

Firstly, the Darby report on Haemophilia and AIDS. If one analyses the actual data produced by Darby et al, it becomes clear that HIV cannot be responsible, at least by itself, for the excess mortality which they observe in HIV+ Haemophiliacs.

Darby observed 403 deaths in HIV+ Haemophliacs between 1985 and 1992. Based on the mortality rate in the HIV- group, they assert that 60 deaths would have been expected. This data they say "suggests that 85% of the deaths in the seropositives were due to HIV infection." (Darby et al. Nature, 7 September 1995). This claim is clearly false.

If one examines the mortality data of their table 3 (p82) one sees that of the 403 deaths in HIV + Haemophiliacs, 235 were attributed to "AIDS, HIV, etc." with no further comment. A total of 168 deaths were from non HIV causes. For example, 72 died from coagulation disorders, a common way for a Haemophiliac to die.

Thus the deaths attributed to "AIDS, HIV, etc." make up 58% of the total, not 85%!!

Further, the death rate due to non 'HIV causes', was three times what they predicted, based on the death rate in the HIV- population. Thus HIV does not explain the excess mortality observed. The HIV orthodoxy proves yet again that they cannot even count.


Secondly, AIDS in Africa.

It is commonly claimed that the reason why there are so few AIDS cases actually reported in Africa is because the disease goes under reported. All diseases are under reported in Africa. Yet compare the reported number of cases of tuberculosis in South Africa between 1980 and 1997.

Reported cases of Tuberculosis in South Africa 1980-1997. Source WHO Global TB report, 1999.

1980 : 55310
1981 : 59943
1982 : 64115
1983 : 62556
1984 : 62717
1985 : 59349
1986 : 55013
1987 : 57406
1988 : 61486
1989 : 68075
1990 : 80400
1991 : 77652
1992 : 82539
1993 : 89786
1994 : 90292
1995 : 86294
1996 : 91578
1997 : 105169

These cases are also under reported, yet they dwarf the number of cases of AIDS that are reported.

Now here is the data for Malaria . As you can see it is incomplete. NA = not available. The reason for this is simply that I cannot find the numbers for that country. This information is from the WHO's Roll Back Malaria website http://mosquito.who.int/cgi-bin/rbm/login_rbm.jsp which is still under construction. The countries marked NA have not yet had the Malaria numbers posted. For those countries which have, one can see that the number of Malaria cases reported for a single year generally dwarfs the number of AIDS cases reported for the entire epidemic. We come back to the same questions again. Kenya which is supposed to have suffered greatly from AIDS, reported 9133 AIDS cases in 1995, and a total 0f 74754 cases since the start of the epidemic. Yet in 1995 the same Kenyan doctors reported 4343190 cases of Malaria according to the WHO. They also reported 28142 TB cases in 1995, and 39738 TB cases in 1997. So if they are being swamped by AIDS, why doesn't this show up in the reports? Why do they report TB and Malaria, but not AIDS?

Country               Year   Reported 
                             Malaria cases

Angola                1995     156603
Belize                1997       4014
Benin                 1997     670857
Botswana              1995      17599
Burkina Faso          1995     501020
Burundi               1995     932794
Cameroon              1997     645309
Cape Verde            1997         20
Central African 
Republic              NA      NA
Chad                  1997     343186
Comoros               1996      15509
Congo                 1997       9491
Cote d'Ivoire         NA      NA
Djibouti              1997       4314
D.R. of Congo         NA      NA
Equatorial Guinea     1995      12530
Eritrea               NA      NA
Ethiopia              NA      NA
Gabon                 1995      35842
Gambia                NA      NA
Ghana                 1997    2227762
Guinea                1997     802210
Guinea-Bissau         NA      NA
Kenya                 1995    4343190
Liberia               NA      NA
Madagascar            NA      NA
Malawi                NA      NA
Mali                  1997     384907
Mauritania            NA      NA
Mauritius             NA      NA
Mozambique            NA      NA
Namibia               1996     425185
Niger                 1997     978855
Nigeria               1997     616466
Rwanda                1997    1210775
Sao Tome and 
Principe              NA      NA
Senegal               NA      NA
Sierra Leone          NA      NA
Somalia               NA      NA
South Africa          1996     29160
Sudan                 NA      NA
Swaziland             NA      NA
Tanzania              1997    1131655
Togo                  NA      NA
Uganda                NA      NA
Zambia                1996    3215866
Zimbabwe              NA      NA


Thirdly, some comments about the well know paper Piatak et al Science (Vol 259, 19 March 1993), which introduces the Q-PCR measurment for 'viral load'. This is the one where they claim to demonstrate large amounts of non infectious HIV in plasma using PCR.

You may recall that they make the claim (p1752): "Circulating levels of of plasma virus determined by QC-PCR also correlated with, but exceeded by an average of 60000 fold, titers of infectious HIV-1". This claim has always bothered me, because I could not see from their data how the infectious virus and QC-PCR numbers could possibly be correlated. A lot of other people have been equally disturbed, so I decided to test the claim statistically.

To do this I loaded all the data into an Excel spread sheet (which I can send you) and determined the actual correlation coefficient, r, between infectious virus and HIV RNA. Recall that if two random variables X and Y are linearly related, i.e. Y = aX + b, then their correlation coefficient is 1 (one). Consequently, since total infectious virus is a fraction of the total virus (a linear relationship if ever there was one), we would expect that the correlation coefficient between the infectious virus and plasma RNA would equal 1, or at least be very close to it. Assuming that is, that the plasma RNA numbers actually measure the total amount of circulating virus.

It isn't. It is actually = 0.102. Yes, r = 0.102. Consequently r^2 = 0.01. If you are not familiar with statistics, let me explain that the square of the correlation coefficient is the important number. It tells you what fraction of the variation in one quantity is explained by the variation of the other. Since here r^2 = 0.01, then the variation in the plasma RNA explains only 1% of the variation in the infectious virus. The claim that these two quantities are correlated is therefore incredibly dubious, and that is being generous. An r^2 value of 0.01 is as close to genuine _non correlation_ as you are ever going to get, and suggests strongly that the HIV RNA by PCR numbers and the infectious virus numbers are independent random variables. That is, the RNA numbers determined by Q-PCR, have little or nothing to do with actual virus, infectious or otherwise. Of course we already knew this, but it is nice to see it confirmed statistically.

The same is true for the CD4 data. For HIV RNA and CD4 numbers, we have r^2 = 0.017. So variation in HIV RNA explains only 1.7% of the variation in CD4 count. The same is true for infectious virus and CD4, there r^2 = 0.03. Again, these random variables, CD4, RNA and infectious virus, appear to be essentially independent random variables. I wonder why Piatak and his colleagues did not discuss this in the paper, along with the implications for the HIV/AIDS hypothesis?

You might also point out that of the 66 subjects enrolled in the Piatak study, a total of 35 had a Tissue Culture Infectious Dose for HIV of 0(zero). 57 had fewer than 1000 infectious virions. This data confirms yet again that HIV fails the Koch postulates. Most HIV seropositive people have no detectable infectious virus. That ought to be the end of the matter.

I hope these observations are of use to you.

Keep up the good work.

Kind regards

Mark Craddock PhD
Senior Research Associate
School of Mathematical Sciences
University of Technology Sydney
Australia.



HEAL
TORONTO

tel/fax:(416) 406-HEAL

Webmaster: Robert Johnston
jaunts@mailcity.com